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. 2016 Apr 21;6:24496. doi: 10.1038/srep24496

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Copyright © 2016, Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Top overrepresented non-cancer Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways from DIANA-mirPath v3.0 analysis, based on miRNAs (A) significantly present in both IM- and aerosol-challenged rhesus macaques, (B) correlated with viral load in rhesus macaques and humans, and (C) selected by best-performing support vector machine model. Significant pathways were determined using the union of predicted miRNA target genes.