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. 2016 Apr 21;6:24267. doi: 10.1038/srep24267

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Copyright © 2016, Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Representative images show endothelial expression of HSP27 (A) in fetal thymus and HSP70 (B) in adult thymus with regular morphology (*asterisk). cTECs with intense subcapsular expression of HSP27 (C) in fetal thymus and HSP70 (D) in FTH is shown (arrows). mTECs and HCs express HSP27 (E) and HSP70 (F) in fetal thymus. Arrows indicate HCs. Staining of HSP27 (G) and HSP70 (H) in dendritic cells of GCs (GC) and TECs in MZ-like distribution (MZ) in FTH is shown. Arrows indicating HSP expressing dendritic cells in GCs (A-F, H: 400x magnification; G: 200x magnification). Hematoxylin was used for counterstaining.HSP27, Heat Shock Protein 27; HSP70, Heat Shock Protein 70; cTEC, cortical Thymic Epithelial Cells; mTEC, medullary Thymic Epithelial Cells; FTH, Follicular Thymic Hyperplasia; HC, Hassall’s Corpuscles; GC, Germinal Center; MZ, TECs with marginal zone like distribution.