TABLE 1.
Clinical and demographic characteristics of women randomized to 17-alpha hydroxyprogesterone caproate or placebo
| Description | Value | 17OHP-C N = 294 (%) |
Placebo N = 149 (%) |
P value |
|---|---|---|---|---|
| No. of previous preterm deliveries | Mean (SE) | 1.40 (0.04) | 1.61 (0.07) | .016 |
| >1 Previous preterm delivery | >1 | 83 (28.23) | 63 (42.28) | .004 |
| ≥1 Previous term deliveries | ≥1 | 145 (49.32) | 69 (46.31) | .615 |
| Gestational age at randomization, wk | Mean (SE) | 18.9 (0.09) | 18.8 (0.12) | .581 |
| Maternal age, y | Mean (SE) | 26.1 (0.31) | 26.6 (0.43) | .382 |
| Race | Black | 177 (60.20) | 89 (59.73) | .862 |
| Caucasian | 74 (25.17) | 34 (22.82) | ||
| Hispanic | 38 (12.93) | 23 (15.44) | ||
| Other/unknown | 5 (1.70) | 3 (2.01) | ||
| Marital status | Married/living with partner | 149 (50.68) | 69 (46.31) | .629 |
| Divorced/widowed/separated | 29 (9.86) | 18 (12.08) | ||
| Never married | 116 (39.46) | 62 (41.61) | ||
| Years of school completed | Mean (SE) | 11.8 (0.13) | 12.0 (0.19) | .379 |
| Smoked during pregnancy | Yes | 65 (22.11) | 30 (20.13) | .713 |
| Drank alcohol during pregnancy | Yes | 26 (8.84) | 10 (6.71) | .469 |
17OHP-C, 17-alpha hydroxyprogesterone caproate.