Fig. 5.

LncRNA Saf overexpression in erythroblasts reduces surface expression of Fas. Human CD34⁺ cells from a single healthy donor were transduced using mock conditions or with lentiviral vector particles encoding for Saf. Flow cytometry histograms demonstrating surface levels of Fas receptor for mock (orange) and Saf (blue) transduced cells collected on days 6 and 10 post-transduction, times corresponding to proliferation and differentiation stages of culture. Dotted line depicts cells reacted with isotype control antibodies.