Table 3. Eleven NHRs that change satiety quiescence and fat storage when knocked down.
RNAi | Quiescence ratio to control (%) | ORO | pORO | pSQ |
---|---|---|---|---|
Group 1: Both decreased | ||||
nhr-170 | 0.62 | less fat | *** | *** |
nhr-206 | 0.45 | less fat | ** | *** |
Group 2: Both increased | ||||
nhr-21 | 1.62 | more fat | *** | *** |
nhr-64 | 1.74 | more fat# | *** | |
Group 3: SQ increased, Fat decreased | ||||
nhr-8 | 1.26 | less fat | * | *** |
nhr-50 | 3.53 | less fat | *** | *** |
nhr-99 | 1.69 | less fat | *** | ** |
nhr-120 | 2.04 | less fat | ** | *** |
nhr-144 | 2.26 | less fat | *** | *** |
Group 4: SQ decreased, Fat increased | ||||
nhr-162 | 0.64 | more fat | ** | *** |
nhr-212 | 0.44 | more fat | *** | *** |
No or weak correlation | ||||
nhr-18 | 1.00 | less fat | *** | N.S |
nhr-36 | 1.12 | less fat | *** | N.S |
nhr-117 | 0.90 | less fat | *** | N.S |
nhr-143 | 0.85 | more fat | *** | N.S |
nhr-163 | 0.84 | more fat | *** | N.S |
nhr-232 | 1.03 | more fat | *** | N.S |
nhr-79 | 2.09 | no change | N.S | *** |
nhr-90 | 1.73 | no change | N.S | *** |
nhr-110 | 1.76 | no change | N.S | *** |
nhr-211 | 0.60 | no change | N.S | *** |
nhr-32 | 1.30 | less fat | ** | N.S |
nhr-40 | 1.18 | no change | N.S | N.S |
nhr-59 | 0.98 | more fat | * | N.S |
nhr-101 | 1.54 | less fat | * | * |
nhr-109 | 1.17 | no change | N.S | * |
nhr-122 | 1.27 | no change | N.S | N.S |
nhr-133 | 1.15 | no change | N.S | N.S |
#Result based on the report by Liang et al.31.
Quiescence ratio is normalized to the concurrent control (see Materials and Methods). 12–25 samples were tested for each RNAi and 7–10 samples for the control. ORO is oil red O staining, pORO is statistical significance for oil red O staining. pSQ is statistical significance for satiety quiescence. *p < 0.05, **p < 0.01, ***p < 0.001 by Student’s t test.