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. 2016 Mar 28;6(1):56–66. doi: 10.1556/1886.2016.00005

Fig. 6.

Fig. 6.

Changes in ileal mucin-2 mRNA levels in gnotobiotic IL-10–/– mice following A. butzleri infection. Gnotobiotic IL-10–/– mice were generated by antibiotic treatment and perorally infected either with A. butzleri strain CCUG 30485 (circles) or strain C1 (squares). Uninfected mice served as negative control (naive; closed diamonds). Mucin-2 mRNA levels were determined in ex vivo ileal biopsies taken at days (d) 6 (closed symbols) or 16 (open symbols) postinfection. Medians (black bars), numbers of analyzed animals, and significance levels as determined by the Mann–Whitney U test are indicated (*p < 0.05). Data shown were pooled from three independent experiments