Table 3.
Association of ppFEV1 and Pulmonary Exacerbations with EQ-5D Index and VAS
| Parameter | Model 1: ppFEV1 Only | Model 2: ppFEV1 + Any PE | Model 3: ppFEV1 + PE Type |
|---|---|---|---|
| EQ-5D Index | |||
| Intercept | 0.670 (0.068)** | 0.678 (0.067)** | 0.686 (0.067)** |
| ppFEV1 | 0.580 (0.193)** | 0.561 (0.193)* | 0.535 (0.193)* |
| ppFEV1 squared | −0.305 (0.135)** | −0.294 (0.135)* | −0.274 (0.135)* |
| Any PE | – | −0.026 (0.013)* | – |
| PE (Hospitalization) | – | – | −0.070 (0.020)* |
| PE (No Hospitalization) | – | – | 0.001 (0.016) |
| EQ-5D VAS | |||
| Intercept | 57.79 (2.38)** | 58.46 (2.36)** | 58.48 (2.36)** |
| ppFEV1 | 32.14 (3.23)** | 31.52 (3.21)** | 31.49 (3.21)** |
| Any PE | – | −4.4 (1.08)** | – |
| PE (Hospitalization) | – | – | −3.82 (1.69)* |
| PE (No Hospitalization) | – | – | −4.75 (1.34)** |
Abbreviations: PE pulmonary exacerbation, ppFEV 1 percent predicted forced expiratory volume in 1 second, VAS visual analog scale
*p < 0.05 **p < 0.001