Table 5.
Baseline characteristics of the RTC study participants
Characteristic | PPARγ2 Pro12 (n = 18) | PPARγ2 12Ala (n = 7) | P-valuesd | ||
Median | Range | Median | Range | ||
Agea, years | 58.5 | (49–70) | 55 | (47–67) | 0.28 |
Weight, kg | 64.1 | (50.1–86.5) | 59.8 | (57.2–68.4) | 0.27 |
BMI, kg/m2 | 23.5 | (19.1–26.9) | 22.4 | (19.4–24.5) | 0.14 |
Years since last menses | 5.5 | (1–25) | 6 | (3–16) | 0.46 |
Alcohol intake/week | 6.5 | (1–15) | 6 | (3.5–14) | 0.70 |
Characteristic | PPARγ2 Pro12 (n = 18) | PPARγ2 12Ala (n = 7) | |||
No. | % | No. | % | ||
Menopause type | |||||
Naturalb | 17 | 94.4 | 6 | 85.7 | |
Hysterectomyc | 1 | 6.6 | 1 | 14.3 | |
Smoking status | |||||
Never | 10 | 55.6 | 5 | 71.4 | |
Former | 8 | 44.4 | 2 | 28.6 |
Characteristics of participants from the RCT divided by genotype
aOne participant was only 48 years, but had not had her menses for 6 years. All other participants were older than 50 years
bOne participant had had a unilateral oophorectomy
cOne participant had a combined hysterectomy and oophorectomy; and one participant had a hysterectomy before last menses, but was older than 60 years
d P-values for comparison of baseline characteristics using Student’s t-test