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. 2016 Apr 21;16:283. doi: 10.1186/s12885-016-2317-y

Table 5.

Baseline characteristics of the RTC study participants

Characteristic PPARγ2 Pro12 (n = 18) PPARγ2 12Ala (n = 7) P-valuesd
Median Range Median Range
Agea, years 58.5 (49–70) 55 (47–67) 0.28
Weight, kg 64.1 (50.1–86.5) 59.8 (57.2–68.4) 0.27
BMI, kg/m2 23.5 (19.1–26.9) 22.4 (19.4–24.5) 0.14
Years since last menses 5.5 (1–25) 6 (3–16) 0.46
Alcohol intake/week 6.5 (1–15) 6 (3.5–14) 0.70
Characteristic PPARγ2 Pro12 (n = 18) PPARγ2 12Ala (n = 7)
No. % No. %
Menopause type
 Naturalb 17 94.4 6 85.7
 Hysterectomyc 1 6.6 1 14.3
Smoking status
 Never 10 55.6 5 71.4
 Former 8 44.4 2 28.6

Characteristics of participants from the RCT divided by genotype

aOne participant was only 48 years, but had not had her menses for 6 years. All other participants were older than 50 years

bOne participant had had a unilateral oophorectomy

cOne participant had a combined hysterectomy and oophorectomy; and one participant had a hysterectomy before last menses, but was older than 60 years

d P-values for comparison of baseline characteristics using Student’s t-test