Fig. 3.

Chimeric var genes. a For all clone lines, there is twofold increase coverage for the second part of PF3D7_1240400 (dark blue) and the first part of the adjacent gene, PF3D7_1240600 (light blue). The duplication-chimera was formed by the fusion of the half of PF3D7_1240600 and half of PF3D7_1240400, the var gene immediately adjacent. b For F12, a twofold increase coverage was observed for the second part of PF3D7_0421100 (green), and the first part of the adjacent gene, PF3D7_0421300 (dark blue) indicating a duplication-chimera formed by duplicating half of PF3D7_0421100 and the other half of PF3D7_0421300. For the A4 and 3D7A strains an increased coverage of the second half of PF3D7_0420700, the full genes PF3D7_0420900 and PF3D7_0421100 and first half of gene PF3D7_0421300, was observed. This indicates a duplication of the genes PF3D7_0420900 and PF3D7_0421100 and a chimeric gene formed by duplicating half of PF3D7_0420700 and half of PF3D7_0421300. c For 3D7A, there is twofold increase coverage for the second part of PF3D7_0712300 (light blue), the whole of PF3D7_0712400 (lilac) and the first part of the adjacent gene PF3D7_0712600 (dark blue). It indicates a duplication of the full gene PF3D7_0712400 and a duplication-chimera formed by duplicating half of PF3D7_0712300 and half of PF3D7_0712600; d For A4, there is twofold increase in coverage of several regions of PF3D7_0412400 (light blue) and PF3D7_0412700 (dark-blue) only for A4. It indicates a chimeric gene formed by multiple cross-overs between the two adjacent genes