Table 1.
Genome sequencing and genetic variation
Clone | Number of read pairs (Millions)b | Median coveragec | % genome with at least 5× coverage | Genetic variationd | ||
---|---|---|---|---|---|---|
SNPs | Indels | Structural variants | ||||
3D7A | 24.6 | 124 | 99.9 | 98 | 143 | 66 |
F12a | 24.1 | 118 | 99.9 | 103 | 157 | 51 |
A4a | 18 | 132 | 99.9 | 104 | 168 | 44 |
aGametocyte non-producers
bFrom Illumina GA II 76 bp paired-end
cMapped to 3D7 version 3.0 and excluding multi-copy apicoplast and mitochondria
dTotal variation per sample, including shared genetic variation but only polymorphisms located in non-sub-telomeric and unique regions