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. 2016 Apr 21;11:30. doi: 10.1186/s13024-016-0093-4

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© Kim et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 8 — SP600125 protected against I/R-induced cell loss in the GCL. Total cell numbers in the GCL were counted from retinas of vehicle or SP600125-treated animals at 28 days after I/R injury. Non-injured contralateral eyes were also analyzed for comparison. I/R injury induced significant GCL cell loss (30.0 ± 5.6 %) compared to contralateral non-injured eyes whereas SP600125 administration showed total protection. Data represent mean ± SEM (n = 5). *: p < 0.05; NS: non-significant between contralateral control and I/R eyes by two-tailed, paired Student’s t-test