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. Author manuscript; available in PMC: 2017 Mar 18.
Published in final edited form as: Curr Protoc Pharmacol. 2016 Mar 18;72:9.19.1–9.19.19. doi: 10.1002/0471141755.ph0919s72

Table 9.19.1.

ABBREVIATIONS USED IN THIS UNIT

a dose of drug A
A dose of drug A that gives a specified effect
A50 dose of drug A that gives half of its maximum effect
Aeq(b) drug A equivalent of dose (b) of drug B
Ai most general designation for dose of drug A that gives effect level i
b dose of drug B
B dose of drug B that gives a specified effect
B50 dose of drug B that gives half of its maximum effect
Beq(a) drug B equivalent of dose (a) of drug A
Bi most general designation for dose of drug B that gives effect level i
C potency constant in common dose response equation
D dose
D50 Dose of a drug that gives half its maximum response
DRC Dose-response curve
E Effect
ED50 Dose that is effective in 50% of subjects
Emax Maximum effect of a drug
f(a) g − 1 + gA/a, a simplifying term
Fa fractional effect due to dose a of drug A
Fb fractional effect due to dose b of drug B
Fab fractional effect due to combination (a,b) dose
g ratio Emax(b)/Emax(a)
p exponent (on dose) in dose-response equation
q exponent (on dose) in dose-response equation
pA proportion of the quantity (total dose) that is drug A in a combination
pB proportion of the quantity (total dose) that is drug B in a combination
Var variance
Zadd Total drug quantity in an additive combination