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. Author manuscript; available in PMC: 2016 May 13.
Published in final edited form as: J Am Chem Soc. 2015 May 4;137(18):6044–6052. doi: 10.1021/jacs.5b01968

Figure 5. Proposed biosynthetic scheme for reductasporine (2).

Figure 5

The tandem action of reductase RedE and methyltransferase RedM is proposed to be key in the formation of 2 from a common indolocarbazole intermediate.