TABLE 2.
Univariate Survival Associations Between the Framingham Risk Score Risk Factors and 10-Y Coronary Heart Disease Riska,b
| Risk factor | Model 1: Univariate model
|
|
|---|---|---|
| HR | 95% CI | |
| Age | 1.09 | 1.08–1.10 |
|
| ||
| Blood pressure (mm Hg) | ||
| Optimal (SBP<120, DBP<80) | 0.67 | 0.51–0.88 |
| Normal (SBP<130, D<85) | 1.00 | – |
| High normal (SBP<140, DBP<90) | 1.36 | 1.06–1.76 |
| Stage I HTN (SBP<160, DBP<100) | 1.55 | 1.23–1.97 |
| Stage II–IV HTN (SBP≥160, DBP≥100) | 1.34 | 0.89–2.04 |
|
| ||
| Total cholesterol level (mg/dL) | ||
| <160 | 0.77 | 0.47–1.26 |
| 160–199 | 1.00 | – |
| 200–239 | 1.87 | 1.47–2.38 |
| 240–279 | 2.89 | 2.22–3.75 |
| ≥280 | 3.03 | 2.14–4.31 |
|
| ||
| HDL-C level (mg/dL) | ||
| <35 | 1.82 | 1.35–2.46 |
| 35–44 | 1.33 | 1.01–1.76 |
| 45–49 | 1.00 | – |
| 50–59 | 0.89 | 0.64–1.23 |
| ≥60 | 0.64 | 0.43–0.96 |
|
| ||
| Diabetes | 3.54 | 2.31–5.42 |
|
| ||
| Current smoking | 1.51 | 1.22–1.87 |
a
DBP = diastolic blood pressure; HDL-C = high-density lipoprotein cholesterol; HR ¼ hazard ratio; HTN = hypertension; SBP = systolic blood pressure.
b
SI conversion factor: To convert mg/dL values to mmol/L, multiply by 0.0259.