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. Author manuscript; available in PMC: 2016 Apr 21.
Published in final edited form as: Mayo Clin Proc. 2015 Oct;90(10):1372–1379. doi: 10.1016/j.mayocp.2015.07.017

TABLE 3.

Crude and Adjusted Associations Between CRF, FRS, and CHDa

Risk factor Model 1: Univariate model
Model 2b: Multivariable model
HR 95% CI HR 95% CI
10-y CHD riskc
 Low 1.00 1.00
 Moderate or high 5.66 4.25–7.55 5.38 4.03–7.19

CRF
 Low 1.00 1.00
 Moderate 0.93 0.71–1.22 0.98 0.75–1.30
 High 0.67 0.51–0.88 0.74 0.56–0.98
a

CHD = coronary heart disease; CRF = cardiorespiratory fitness; FRS = Framingham Risk Score; HR = hazard ratio.

b

Model 2 investigates the association between CRF (categorized into low, moderate, and high) and CHD events while controlling for moderate or high 10-y CHD risk and baseline examination year.

c

Low or moderate or high 10-y CHD risk is a comparative risk calculated from the summation of FRS points. Moderate or high risk is defined as a sum of >5 points.