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. 2015 Dec 18;5(4):e1112942. doi: 10.1080/2162402X.2015.1112942

Table 1.

 

In situ source of PAMPs Immunostimulatory partner Cancer types Trial
T-vec (Herpes simplex virus type 1 oncolytic virus, Amgen) Anti-CTLA-4 (ipilimumab, BMS) Melanoma NCT01740297
Anti-PD-1 (pembrolizumab, Merck) Melanoma NCT02263508
radiation STS NCT02453191
DNX-2401 (Oncolytic adenovirus, DNAtrix) IFNγ Glioblastoma NCT02197169
HF10 (HSV1 oncolytic virus, Takara) Anti-CTLA-4 (ipilimumab, BMS) Melanoma NCT02272855
CAVATAK (Oncolytic Coxsackievirus A21, Viralytics) Anti-CTLA-4 (ipilimumab, BMS) Melanoma NCT02307149
BCG Mycobacterium bovis Anti-CTLA-4 (ipilimumab, BMS) Melanoma NCT01838200
Poly-ICLC (TLR7–8 agonist, Oncovir) Flt3-Ligand (CDX-301, Celldex) B cell Lymphoma NCT01976585
SD-101 (TLR9 agonist , Dynavax) Anti-CTLA-4 (ipilimumab, BMS) B cell Lymphoma NCT02254772
radiation B cell Lymphoma NCT02266147