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. 2015 Nov 25;5(4):e1100788. doi: 10.1080/2162402X.2015.1100788

Figure 5.

Figure 5.

Serum concentration of cytokines during treatment. a) left: IL6 levels increased from baseline to 4th series (p = 0.008). Middle: IL6 level at baseline were higher in patients with continued progression despite treatment as compared to clinical responders (SD, PR and CR, p = 0.09). Right: Level of IL6 at baseline correlated to the cytokine level by the 4th series. b) Above median levels of IL6 by the 4th series were associated with reduced survival (log rank, p = 0.07). c) Serum concentration of TNF, IFN-γ, IL2, IL4, IL10 and IL17A at baseline and during treatment.