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. 2015 Oct 29;5(4):e1105429. doi: 10.1080/2162402X.2015.1105429

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© 2016 The Author(s). Published with license by Taylor & Francis Group, LLC

This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License http://creativecommons.org/licenses/by-nc/3.0/, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.

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Figure 7. — Efficacy of PeptiCRAd in humanized mice bearing human melanomas. Humanized and non-humanized mice bearing SK-MEL-2 human melanomas were treated with one of the following: (i) saline solution (mock), (ii) Ad5D24-GM-CSF, and (iii) MAGE-A1 PeptiCRAd. The tumor volume of the humanized mice (A) is presented as the mean ± SD (n = 3). (B) The area under the curve (AUC) relative to the size of the tumors of humanized-mice is presented. (C) The tumor volume of non-humanized mice (n = 2) is reported as the mean ± SD. (D) Percentage of MAGE-A1-specific CD8⁺ T cell population is presented as the mean ± SD (n = 2). Mann-Whitney test; *p < 0.05.