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. 2015 Nov 10;5(3):e1100791. doi: 10.1080/2162402X.2015.1100791

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© 2016 The Author(s). Published with license by Taylor & Francis Group, LLC

This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.

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Figure 5. — Modulation of IL-17A and IL-21 production by CD4⁺ CD45RA^neg T cells detected in periphery during breast tumor progression. The capacity of CD4⁺ CD45RA^neg T cells to produce IL-17A or IL-21 was assessed in WB after short-term polyclonal stimulation (P/I) in presence of brefeldin A on cohorts of patients with breast cancers at different stage of disease (PT (n = 46), FR (n = 34), SR (n = 20)) and compared to a HD cohort (n = 31) Results are presented as percentage of CD4⁺ CD45RA^neg T cells producing IL-17A (A) or IL-21 (B) or co-producing IL-21 and TNFα, IL-21 and IFNγ or IL-21 and IL-2 (C). * p value< 0.05, **: p value < 0.01.