Table 1.

Patients' characteristics.

	Healthy donors	Primary tumors	First relapse	Second relapse
N	30	46	34	20
Age [min–max]	51 years [34–63]	44 years [29–63]	55 years [32–77]	60 years [39–76]
Histologic type		n (%)	n (%)	n (%)
Missing data		1		1
Lobular carcinoma		2 (4.4%)	6 (17.6%)	3 (15.8%)
Ductal carcinoma		43 (95.6%)	28 (82.4%)	16 (84.2%)
ER/PgR status
ER+		26 (56.5%)	27 (79.4%)	15 (75%)
PgR+		23(50%)	25 (73.5%)	9 (45%)
HER2 status
Positive		7 (15.2%)	1 (2.9%)	2 (10%)
Triple-negative tumors		17 (36.9%)	6 (17.64%)	4 (20%)
SBR status
Missing data				1
1			3 (8.8%)
2		23 (50%)	16 (47.1%)	10 (52.6%)
3		23 (50%)	15 (44.1%)	9 (47.4%)
Number of metastatic LN
missing data		5	5
<3		37 (80.4%)	15 (44.1%)	7 (35%)
≥3		9 (19.6%)	14 (41.2%)	13 (65%)
Main metastatic sites
Bone		0	15 (44.11%)	16 (80%)
Liver		0	14 (41.17%)	13 (65%)
Bone only		0	2 (5.88%)	1 (5%)