Fig. S3.

Firing properties of SNc neurons are not related to their location within the nucleus. (A–D, Left and Center) Firing properties [baseline firing rate (A), variability in firing rate (B), minimum firing rate at movement (C), and maximum firing rate premovement (D)] of SNc neurons from wild-type and Snca^−/− mice were plotted according to their ML (Left) or AP (Center) positions in the SNc and were fit with a least-squares regression. R² and P values from a Pearson product–moment correlation (n = 26 SNc neurons) are given. (A–D, Right) Firing property heat maps were constructed by dividing the SNc into 50-µm² segments. The color represents the mean value of all neurons within each segment. There were no significant relationships between ML or AP position or the mean firing rate of SNc dopamine neurons during the baseline period before movement (A), firing variability at rest (B), the minimum z-scored firing rate reached in the 160 ms following the start of movement onset (C), or the maximum z-scored firing rate during the 160 ms preceding movement (D).