Table 2. Between-Group Comparisons of BOLD Activation in Response to OCD-Specific Words Relative to Neutral Words.
Brain region (Brodmann area) |
MNI coordinates |
Z-score | Cluster size | ||
---|---|---|---|---|---|
x | y | z | |||
OCD >non-OCD | |||||
L medial superior frontal cortex (10) | −14 | 62 | 2 | 4.79 | 678 |
−4 | 58 | 20 | 4.73 | ||
R rostral anterior cingulate cortex (32) | 10 | 50 | 10 | 4.1 | |
R precuneus (23) | 8 | −58 | 30 | 4.17 | 215 |
L precuneus (23) | −10 | −52 | 36 | 3.9 | |
−6 | −52 | 26 | 3.59 | ||
L parieto-occipital cortex (39) | 36 | −62 | 24 | 4.01 | 41 |
38 | −68 | 18 | 3.63 | ||
L middle temporal cortex (39) | −46 | −70 | 18 | 3.92 | 128 |
L angular cortex (39) | −50 | −66 | 32 | 3.82 | |
L middle temporal cortex (39) | −46 | −58 | 22 | 3.53 | |
R caudate | 18 | 14 | 10 | 3.87 | 137 |
R putamen | 26 | 16 | 6 | 3.63 | |
28 | 14 | −4 | 3.62 | ||
R amygdala | 20 | 6 | −10 | 3.86 | 29 |
L insula (48) | −26 | 16 | −8 | 3.84 | 24 |
R precuneus (23) | 20 | −54 | 24 | 3.63 | 43 |
Non-OCD >OCD | |||||
None |
Abbreviations: BOLD, blood oxygen level dependent; L, left; MNI, Montreal Neurological Institute; OCD, obsessive–compulsive disorder; R, right.