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(a) KO mice show a resistance to MK-801-induced PPI disruptions. Environmental enrichment reinstated the normal response and increased sensitivity to MK-801 in KO mice. (b) MK-801 did not alter startle amplitude in WT or KO mice. Data expressed as mean±SEM of 9–15 mice per group; *p<0.05, **p<0.01 (genotype).
