Figure 4.
Exendin-4 (Ex4; 1 μg/kg, i.p.) significantly prolonged meal duration in both groups but did not prolong pauses between bursts of licking. (a) Mean meal duration (+SEM) after vehicle (saline) or exendin-4 (Ex4) injection in intact sham-lesioned rats (PBNsham) and rats with ibotenic-acid lesions of the PBN (PBNx). Ex4 significantly prolonged the meal in both groups. (b) Mean pause duration (+SEM) after vehicle or Ex4 injection in PBNsham and PBNx rats. Ex4 did not affect the mean interval between bursts of licking in either lesion group. *P<0.05.