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. 2016 Feb 14;84(1):113–130. doi: 10.3797/scipharm.ISP.2015.04

Fig. 6.

Fig. 6

The influence of treatment on the HepG2 cell cycle. A. Flow cytometric analysis ilustrating celullar DNA content. DNA histogram number 1= control, 2= native rIFNα2b, 3= mutein rIFNα2b (C2D C99D); B. The percentage of cell number in different phase of cycles. Protein concentration was 5 ug/mL and treatment time was 72 h. The mutein rhIFNα2b tends to show better proapoptotic activity.