Fig 3. Patients with hematological malignancies have specific NK cell subset profiles that correlate with maturation status.
PBMCs from blood samples (bs) of healthy donors and of patient with different hematological cancers or from bone marrow (bms) of the patient with MM or AML were stained as in Fig 2. The percentage of CD45RA, CD45RARO, CD45RAdim and CD45RAdimRO cells at the different stage of NK maturation (CD56/16 expression) was depicted in the graphic. Each point represents a donor. The mean ± SD and the statistical analysis are also shown. HD, Healthy donor; MM, multiple myeloma; B-CLL, B-cell chronic lymphocytic leukemia; BCL, B-cell lymphoma; AML, acute myeloid leukemia; bs, blood samples; bms, bone marrow samples.