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. 2016 Apr 21;12(4):e1006001. doi: 10.1371/journal.pgen.1006001

Fig 4. TGF-ß signals regulate the dorsoventral pattern of hbn.

Fig 4

(A-E) hbn is shifted toward the dorsal side, where serotonergic neurons are differentiated (E) in control embryos. (F-J) hbn surrounds the foxQ2 region and the serotonergic neurons are differentiated at the same region (J). Clear shifting toward the edge of the AP and strongly localized expression at later stages is not observed in Lefty morphants (K-O) or BMP2/4 morphants (P-T). Both have no serotonergic neurons. Asterisks indicate the precursors of serotonergic neurons, which express zfhx1.