Table 1. Binning statistics.
| TR | EX | C0902 | ||||
|---|---|---|---|---|---|---|
| Statistic | on-target | off-target | on-target | off-target | on-target | off-target |
| Number of bins | 8,216 | 19,434 | 301,249 | 55012 | 8,662 | 19,402 |
| Total bin footprint (bp) | 1,791,315 | 2,837,786,301 | 70,364,091 | 2,468,075,581 | 1,867,888 | 2,837,005,032 |
| Mean bin size (bp) | 218.0 | 146,021.7 | 233.6 | 44864.3 | 215.6 | 146,222.3 |
| Min. bin size (bp) | 36 | 10,012 | 114 | 6,000 | 42 | 10,089 |
| 1st quartile bin size (bp) | 183 | 148,196 | 197 | 11,304 | 181 | 148,108 |
| Median bin size (bp) | 203 | 149,819 | 227 | 28,358 | 200 | 149,814.5 |
| 3rd quartile bin size (bp) | 259 | 151,062 | 268 | 86,767 | 257 | 151,070 |
| Max. bin size (bp) | 397 | 223,781 | 399 | 134,972 | 398 | 224,678 |
The bins for the exome panel (EX) cover a slightly smaller total genomic footprint than the targeted panels (TR, C0902) because most introns are smaller than the minimum size allowed for off-target bins, and thus discarded from the exome bins, while the off-target bins in the targeted panels span both the introns and exons of non-targeted genes.