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. 2016 Apr 21;11(4):e0154186. doi: 10.1371/journal.pone.0154186

Table 1. Relationships between AXL expression and clinical factors in 161 LAD specimens.

Factor AXL expression P*
0 1+ 2+ 3+
n n = 57 n = 32 n = 60 n = 12
Sex Female 87 31 (35%) 17 (20%) 33 (38%) 6 (7%) 0.77
Male 74 26 (35%) 15 (20%) 27 (37%) 6 (8%)
Age (years) < 69 82 26 (32%) 20 (24%) 30 (37%) 6 (7%) 0.95
≥ 69 79 31 (39%) 12 (15%) 30 (38%) 6 (8%)
CEA < 5.0 103 38 (37%) 18 (17%) 41 (40%) 6 (6%) 0.25**
≥ 5.0 54 17 (31%) 14 (26%) 17 (31%) 6 (12%)
unknown 4 2 (50%) 0 (0%) 2 (50%) 0 (0%)
P-stage I 111 40 (36%) 24 (22%) 38 (34%) 9 (8%) 0.82
II 25 9 (36%) 3 (12%) 12 (48%) 1 (4%)
III 23 8 (35%) 5 (22%) 8 (35%) 2 (8%)
IV 2 0 (0%) 0 (0%) 2 (100%) 0 (0%)
Smoking Ever 78 27 (35%) 20 (26%) 28 (36%) 3 (3%) 0.084**
Never 72 27 (38%) 11 (15%) 26 (36%) 8 (11%)
Unknown 11 3 (27%) 1 (9%) 6 (55%) 1 (9%)
Grade*** Low 129 44 (34%) 28 (22%) 48 (37%) 9 (7%) 0.62
High 31 12 (39%) 4 (13%) 12 (38%) 3 (10%)

*[0/1+/2+] vs [3+].

**Patients with unknown status were excluded from statistical analysis.

***One case of minimally invasive adenocarcinoma was excluded. CEA: carcinoembryonic antigen, in μg/L.