Fig 3. Shared sequences are found at higher frequencies in peripheral Tconv and Tregs.

A) The sequences and frequencies of the most abundant TCRs in Tconv and Tregs and whether they are shared (gray) or are not shared (uncolored). B) Sequences that are not shared (grey) are found at significantly lower frequencies, while shared sequences (white) are found at significantly higher frequencies in the repertoires. Frequencies are measured as percentage of entire repertoire. Statistical significance was determined using the student’s t-test (n = 5, Mean ± SE, * p<.05, ** p<.01, *** p<0.0001).