Table 1.

Quality of life values

Parameters n (%)	Patients (%) (n=53)¶	Prior use of abiraterone		p value
		No (n=33)	Yes (n=20)
FACT-P ≥16 points*	7 (13.0)	3 (9.1)	4 (20.0)	0.2807
FACT-P ≥10 points*	14 (25.9)	6 (18.2)	8 (40.0)	0.1454
FACT-P ≥6 points*	20 (37.0)	10 (30.3)	10 (50.0)	0.2151
PCS subscale ≥2 points*	26 (50.0)	15 (46.9)	11 (57.9)	0.7011
PCS pain subscale ≥2 points*	12 (23.1)	7 (21.9)	5 (26.3)	0.8505
Pain response rate‡	4 (21.1)	3 (20.0)	1 (25.0)	0.7425

^*Minimally clinically important difference observed on two consecutive cycles where an increase in score on the FACT-P instrument and its subscales indicates improvement in quality of life.

^¶For the FACT-P questionnaire, an evaluable patient is defined as a patient who responds to at least 80 % of the items. FACT–P is a 39-item questionnaire that consists of FACT–G (general), a 27-item self-report questionnaire that measures general health-related quality of life in cancer patients, and the Prostate Cancer Subscale (PCS), a 12-item subscale specifically designed to measure prostate cancer-specific quality of life. The FACT–P total score includes the FACT–G and the PCS. The FACT–P PCS pain-related score includes four questions from the FACT–P interrogating pain specifically.

^‡Pain response was established only for patients with median present pain intensity (PPI) score of 2 or more or mean analgesic score (AS) of 10 points or more at baseline, or both, and was defined as a two-point or greater reduction from baseline median PPI score without an increased AS or a decrease of 50% or more in the AS without an increase in the PPI score, maintained for at least three weeks. FACT-P: Functional Assessment of Cancer Therapy – Prostate.