Table 3.
Histomorphometry
| Tibia | Normal (n=8) | CKD (Vehicle) (n=9) | CKD (Raloxifene) (n=10) | 
|---|---|---|---|
| MAR (μm/day)¶ | 1.305 ± 0.185 | 2.470 ± 0.569 | 1.890 ± 0.511 | 
| MS/BS (%)§ | 26.56 ± 5.14 | 33.32 ± 4.11 | 23.89 ± 4.75 # | 
| BFR/BS (μm3/μm2/year)¶ | 126.65 ± 31.02 | 299.62 ± 74.35 * | 170.40 ± 78.52 # | 
| Oc.S/BS (%)¶ | 7.157 ± 1.250 | 15.739 ± 3.332 * | 15.684 ± 6.857 * | 
| N.Oc/BS (1/mm)§ | 1.966 ± 0.412 | 4.125 ± 0.785 * | 4.134 ± 1.653 * | 
| Vertebra | Normal (n=8) | CKD (Vehicle) (n=9) | CKD (Raloxifene) (n=10) | 
| MAR (μm/day)¶ | 1.057 ± 0.339 | 1.983 ± 0.876 | 1.574 ± 0.400 | 
| MS/BS (%)§ | 13.62 ± 3.98 | 27.81 ± 5.73 * | 16.21 ± 3.73 # | 
| BFR/BS (μm3/μm2/year)¶ | 52.14 ± 21.76 | 211.94 ± 128.49 * | 94.19 ± 39.80 # | 
One-Way ANOVA followed by Fisher’s LSD tests
Kruskal-Wallis test followed Mann-Whitney U tests (with Bonferroni correction)
vs. Normal
vs. CKD (Vehicle)