Table 1a.
Baseline characteristics of recipients of non-diabetic vs. diabetic donor kidneys
| Diabetic Donors N = 9,074* |
Non-Diabetic Donors N = 152,555* |
P-value | |
|---|---|---|---|
| Recipient Characteristics | |||
|
| |||
| Median age in years (IQR) | 56 (47-64) | 51 (41-60) | P < 0.001 |
|
| |||
| Male (%) | 5,612 (61.9) | 92,258 (60.5) | p = 0.009 |
|
| |||
| Race (%) | p < 0.001 | ||
| Caucasian | 4,247 (46.8) | 75,502 (49.5) | |
| African American | 2,915 (32.1) | 45,949 (30.1) | |
| Latino | 1,204 (13.3) | 19,831 (13.0) | |
| Asian | 539 (5.9) | 8,063 (5.3) | |
| Other | 169 (1.9) | 3,210 (2.1) | |
|
| |||
| Cause of ESRD (%) | p < 0.001 | ||
| Diabetes | 2,516 (27.7) | 37,335 (24.5) | |
| Hypertension | 2,606 (28.7) | 37,335 (24.5) | |
| Glomerular Disease | 1,353 (14.9) | 27,169 (17.8) | |
| Cystic Disease | 764 (8.4) | 13,571 (8.9) | |
| Other | 1,350 (14.9) | 27,238 (17.9) | |
| Missing | 485 (5.3) | 9,701 (6.4) | |
|
| |||
| Pre-transplant Dialysis (%) | 8,208 (90.5) | 138,048 (90.5) | p = 0.035 |
|
| |||
| Median Years on Dialysis (IQR) | 3.3 (1.9-5.2) | 3.2 (1.8-5.1) | p < 0.001 |
|
| |||
| Median Total Days on Wait List (IQR) | 688 (293-1208) | 616 (249-1141) | p < 0.001 |
|
| |||
| Repeat Renal Transplant | 797 (8.8) | 16,974 (11.1) | p < 0.001 |
|
| |||
| HBV Surface Ag + (%) | 194 (2.1) | 2,866 (1.9) | p = 0.056 |
|
| |||
| HCV+ Recipient (%) | 457 (5.0) | 8,920 (5.9) | p < 0.001 |
|
| |||
| PRA ≥ 30% (%) | 1,689 (18.6) | 32,831 (21.5) | p < 0.001 |
|
| |||
| ≥ 1 HLA Zero Mismatch (%) | 663 (7.3) | 16,608 (10.9) | p < 0.001 |
|
| |||
| Pre-transplant Diabetes (%) | 3,260 (35.9) | 45,245 (29.7) | p < 0.001 |
|
| |||
| Median BMI (kg/m2) | 27.3 (23.8-31.2) | 26.7 (23.3-30.8) | p < 0.001 |
|
| |||
| Donor Characteristics | |||
|
| |||
| KDPI Percentile (IQR) | 77 (59-90) | 40 (18-64) | p < 0.001 |
|
| |||
| Expanded Criteria Donor (%) | 3,388 (37.3) | 23,026 (15.1) | p < 0.001 |
|
| |||
| HCV+ Donor (%) | 152 (1.7) | 3,776 (2.5) | p < 0.001 |
|
| |||
| Median Donor Age in Years (IQR) | 50 (42-57) | 38 (22-50) | p < 0.001 |
|
| |||
| Median BMI (kg/m2) | 29.7 (25.4-35.0) | 25.2 (22.0-29.2) | p < 0.001 |
|
| |||
| Transplant Characteristics | |||
|
| |||
| Median CIT in Hours (IQR) | 18 (13-25) | 18 (13-24) | p < 0.001 |
|
| |||
| Delayed Graft Function (%) | 2,727 (30.1) | 37,453 (24.6) | p < 0.001 |
|
| |||
| Acute Rejection at One Year (%) | 1,049 (14.9) | 20,516 (17.0) | p < 0.001 |
|
| |||
| Tacrolimus Maintenance (%) | 6,577 (72.5) | 96,268 (63.1) | p < 0.001 |
|
| |||
| Mycophenolate Maintenance (%) | 7,558 (83.3) | 119,925 (78.6) | p < 0.001 |
|
| |||
| No Induction (%) | 2,285 (25.2) | 44,828 (29.4) | p < 0.001 |
|
| |||
| Lymphodepleting Induction (%) | 5,079 (56.0) | 77,424 (50.8) | p < 0.001 |
|
| |||
| Non-Lymphodepleting Induction (%) | 2,073 (22.9) | 35,790 (23.5) | p = 0.179 |
|
| |||
| Both Types of Induction (%) | 363 (4.0) | 5,487 (3.6) | p = 0.045 |
*
N denotes the number of recipients in each donor category