Table 1b.
Baseline characteristics among discordant diabetic and non-diabetic mate-kidney recipients
| Diabetic Donors | Non-Diabetic Donors | ||||
|---|---|---|---|---|---|
|
| |||||
| Diabetic Recipients N = 1,539 |
Non-Diabetic Recipients N = 1,539 |
Diabetic Recipients N = 21,459 |
Non-Diabetic Recipients N = 21,459 |
P-value | |
| Recipient Characteristics | |||||
|
| |||||
| Median age in years (IQR) | 59 (52-65) | 55 (45-64) | 57 (49-63) | 50 (40-60) | p < 0.001 |
|
| |||||
| Male (%) | 1,014 (65.9) | 941 (61.1) | 13.699 (63.8) | 12,916 (60.2) | p < 0.001 |
|
| |||||
| Race (%) | p < 0.001 | ||||
| Caucasian | 652 (42.4) | 747 (48.5) | 9,845 (45.9) | 11,009 (51.3) | |
| African American | 495 (32.2) | 495 (32.2) | 6,599 (30.8) | 6,366 (29.7) | |
| Latino | 268 (17.4) | 268 (17.4) | 3,382 (15.8) | 2,556 (11.9) | |
| Asian | 86 (5.6) | 102 (6.6) | 1,026 (4.8) | 1,151 (5.4) | |
| Other | 38 (2.5) | 15 (1.0) | 607 (2.8) | 377 (1.8) | |
|
| |||||
| Pre-transplant Dialysis (%) | 1,405 (91.3) | 1,368 (88.9) | 19,701 (91.8) | 19,119 (89.1) | p < 0.001 |
|
| |||||
| Median Years on Dialysis (IQR) | 3.2 (1.8-4.9) | 3.4 (1.8-5.4) | 3.0 (1.8-4.7) | 3.2 (1.8-5.2) | p < 0.001 |
|
| |||||
| Median Total Days on Wait List (IQR) | 646 (281-1147) | 717 (302-1228) | 582 (234-1086) | 628 (257-1142) | p < 0.001 |
|
| |||||
| Repeat Renal Transplant | 76 (4.9) | 142 (9.2) | 1,252 (5.8) | 2,516 (11.7) | p < 0.001 |
|
| |||||
| HBV Surface Ag + (%) | 23 (1.5) | 26 (1.7) | 382 (1.8) | 448 (2.09) | p = 0.027 |
|
| |||||
| HCV+ Recipient (%) | 65 (4.2) | 75 (4.9) | 1,194 (5.6) | 1,237 (5.8) | p = 0.054 |
|
| |||||
| PRA ≥ 30% (%) | 222 (14.4) | 302 (19.6) | 3,813 (17.8) | 4,743 (22.1) | p < 0.001 |
|
| |||||
| ≥ 1 HLA Zero Mismatch (%) | 133 (8.6) | 107 (7.0) | 2,322 (10.8) | 2,234 (10.4) | p < 0.001 |
|
| |||||
| Median BMI (kg/m2) | 28.8 (25.5-32.6) | 26.7 (23.3-30.7) | 28.6 (25.1-32.5) | 26.3 (23.1-30.2) | p < 0.001 |
|
| |||||
| Donor Characteristics | |||||
|
| |||||
| KDPI Percentile (IQR) | 78 (60-89) | 44 (21-67) | p < 0.001 | ||
|
| |||||
| Expanded Criteria Donor (%) | 590 (38.3) | 3,788 (17.7) | p < 0.001 | ||
|
| |||||
| HCV+ Donor (%) | 17 (1.1) | 557 (2.6) | p < 0.001 | ||
|
| |||||
| Median Donor Age in Years (IQR) | 50 (43-57) | 42 (26-52) | p < 0.001 | ||
|
| |||||
| Median BMI (kg/m2) | 29.9 (26.0-35.3) | 25.8 (22.5-29.9) | p < 0.001 | ||
|
| |||||
| Transplant Characteristics | |||||
|
| |||||
| Median CIT in Hours (IQR) | 17.8 (13-24) | 17.3 (13-24) | 17.6 (12-24) | 17.2 (12-23) | p = 0.025 |
|
| |||||
| Delayed Graft Function (%) | 517 (33.6) | 406 (26.4) | 6,124 (28.5) | 4,955 (23.1) | p < 0.001 |
|
| |||||
| Acute Rejection at One Year (%) | 175 (14.6) | 152 (12.6) | 2,322 (13.6) | 2,608 (15.1) | p = 0.001 |
|
| |||||
| Tacrolimus Maintenance (%) | 1,182 (76.8) | 1,174 (76.3) | 14,839 (69.2) | 15,008 (69.9) | p < 0.001 |
|
| |||||
| Mycophenolate Maintenance (%) | 1,334 (86.7) | 1,312 (85.3) | 18,099 (84.3) | 18,103 (84.4) | p = 0.075 |
|
| |||||
| No Induction (%) | 372 (24.2) | 330 (21.4) | 5,887 (27.4) | 5,884 (27.4) | p < 0.001 |
|
| |||||
| Lymphodepleting Induction (%) | 825 (53.6) | 866 (56.3) | 10,801 (50.3) | 11,009 (51.3) | p < 0.001 |
|
| |||||
| Non-Lymphodepleting Induction (%) | 413 (26.8) | 395 (25.7) | 5,680 (26.5) | 5,294 (24.7) | p < 0.001 |
|
| |||||
| Both Types of Induction (%) | 71 (4.6) | 52 (3.4) | 909 (4.2) | 728 (3.4) | p < 0.001 |