Table 3.

Cox proportional hazards model for time to all-cause allograft failure in recipients of diabetic vs. non-diabetic donor kidneys

	Univariate Analysis					Multivariable Analysis*
	HR	SE	z	p-value	95% CI	HR	SE	z	p-value	95% CI
Donor Characteristics
Diabetes	1.447	0.025	21.53	< 0.001	1.399-1.497	1.210	0.024	9.67	< 0.001	1.164-1.258
ECD	1.641	0.017	48.56	< 0.001	1.608-1.674	1.573	0.019	37.92	< 0.001	1.537-1.611
Obese (BMI >=30)	1.069	0.011	6.59	< 0.001	1.048-1.091
Recipient Characteristics
Age > 40	1.181	0.011	17.33	< 0.001	1.159-1.203	1.008	0.012	0.67	0.505	0.985-1.031
Male	1.115	0.009	13.09	< 0.001	1.097-1.133	1.073	0.011	7.07	< 0.001	1.052-1.094
African American Race	1.355	0.012	35.29	< 0.001	1.333-1.379	1.333	0.014	28.21	< 0.001	1.306-1.359
Pre-Transplant Dialysis**	1.029	0.001	25.72	< 0.001	1.027-1.032
Time on Waitlist (days)	1.000	0.000	4.89	< 0.001	1.000-1.000
Repeat Renal Transplant	1.048	0.013	3.69	< 0.001	1.022-1.074
HCV+	1.543	0.024	27.86	< 0.001	1.497-1.591	1.458	0.026	21.54	< 0.001	1.409-1.509
Max PRA ≥30	1.081	0.011	7.70	< 0.001	1.060-1.103	1.119	0.014	8.97	< 0.001	1.092-1.146
≥ 1 HLA Mismatch	1.281	0.018	17.95	< 0.001	1.246-1.316
Pre-Transplant Diabetes**	1.015	0.000	39.03	< 0.001	1.014-1.015	1.012	0.000	30.90	< 0.001	1.012-1.013
Obese (BMI >=30)	1.150	0.011	15.31	< 0.001	1.130-1.171
Cold Ischemia Time	1.007	0.000	14.24	< 0.001	1.006-1.008
Delayed Graft Function	1.780	0.016	65.72	< 0.001	1.750-1.811
Acute Rejection at 1 Year	1.592	0.017	43.48	< 0.001	1.559-1.626
No Induction Immunosuppression	1.040	0.009	4.65	< 0.001	1.023-1.058	1.116	0.012	10.57	< 0.001	1.093-1.139

^*Tacrolimus and the interaction term between tacrolimus and time were also included in the multivariable model

^**Included as an interaction term along with duration of dialysis or diabetes, as appropriate