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. Author manuscript; available in PMC: 2016 May 18.
Published in final edited form as: Kidney Int. 2015 Oct 21:10.1038/ki.2015.325. doi: 10.1038/ki.2015.325

Table 4.

Cox proportional hazards model for time to death in discordant diabetic vs. non-diabetic recipient pairs

Univariate Analysis Multivariable Analysis*
HR SE z p-value 95% CI HR SE Z p-value 95% CI
Non-Diabetic Donor
Diabetic Recipient 1.990 0.045 30.72 < 0.001 1.905-2.080 1.932 0.063 20.20 < 0.001 1.812-2.060
Non-Diabetic Recipient REF REF
Diabetic Donor
Diabetic Recipient 1.847 0.156 7.24 < 0.001 1.564-2.180 1.532 0.179 3.64 < 0.001 1.218-1.927
Non-Diabetic Recipient REF REF
Recipient Characteristics
 Age > 40 1.837 0.085 13.21 < 0.001 1.679-2.011 1.928 0.125 10.12 < 0.001 1.698-2.189
 Male 1.118 0.036 3.47 0.001 1.050-1.191 1.025 0.046 0.54 0.591 0.937-1.120
 African American Race 0.996 0.038 −0.12 0.907 0.924-1.072 0.954 0.052 −0.87 0.386 0.858-1.061
 Pre-Transplant Dialysis** 1.058 0.006 9.30 < 0.001 1.046-1.071 1.052 0.009 5.96 < 0.001 1.035-1.070
 Time on Waitlist (days) 1.000 0.000 2.85 0.004 1.000-1.000
 Prior Renal Transplant 1.047 0.059 0.83 0.409 0.938-1.169 1.200 0.102 2.16 0.031 1.017-1.417
 HCV+ 0.647 0.228 −1.24 0.216 0.324-1.291 1.090 0.116 0.81 0.417 0.885-1.343
 Max PRA ≥30 1.162 0.051 3.41 0.001 1.066-1.267
 ≥ 1 HLA Mismatch 1.011 0.071 0.16 0.873 0.881-1.160
 Obese (BMI >=30) 1.036 0.036 1.03 0.304 0.968-1.109
 Cold Ischemia Time 1.007 0.003 2.83 0.005 1.002-1.012
 Delayed Graft Function 1.942 0.043 30.32 < 0.001 1.486-1.734
 Acute Rejection at 1 Year 1.396 0.077 6.03 < 0.001 1.252-1.555
 No Induction
Immunosuppression
0.995 0.039 −0.12 0.906 0.921-1.076
*

Tacrolimus and the interaction term between tacrolimus and time were also included in the multivariable model

**

Included as an interaction term along with duration of dialysis or diabetes, as appropriate