Table 5.

Cox proportional hazards model for time to all-cause allograft failure in discordant diabetic vs. non-diabetic recipient pairs

	Univariate Analysis					Multivariable Analysis*
	HR	SE	z	p-value	95% CI	HR	SE	z	p-value	95% CI
Non-Diabetic Donor
Diabetic Recipient	1.494	0.030	19.73	< 0.001	1.436-1.555	1.445	0.041	13.07	< 0.001	1.367-1.527
Non-Diabetic Recipient	REF					REF
Diabetic Donor
Diabetic Recipient	1.349	0.099	4.06	< 0.001	1.168-1.558	1.269	0.120	2.52	0.012	1.054-1.528
Non-Diabetic Recipient	REF					REF
Recipient Characteristics
Age > 40	1.033	0.039	0.86	0.390	0.959-1.113	1.019	0.051	0.37	0.712	0.923-1.125
Male	1.092	0.032	3.02	0.003	1.031-1.156	1.061	0.042	1.50	0.134	0.982-1.146
African American Race	1.197	0.041	5.29	< 0.001	1.120-1.280	1.250	0.056	4.96	< 0.001	1.145-1.366
Pre-Transplant Dialysis**	1.054	0.006	9.45	< 0.001	1.042-1.065
Time on Waitlist (days)	1.000	0.000	3.07	0.002	1.000-1.000
Repeat Renal Transplant	1.180	0.059	3.30	0.001	1.069-1.301
HCV+	0.941	0.281	−0.20	0.838	0.524-1.690	1.114	0.099	1.22	0.222	0.936-1.326
Max PRA ≥30	1.165	0.046	3.90	< 0.001	1.079-1.258	1.226	0.066	3.80	< 0.001	1.104-1.361
≥ 1 HLA Mismatch	1.139	0.073	2.02	0.043	1.004-1.292
Obese (BMI 7 gt;=30)	1.127	0.035	3.83	< 0.001	1.060-1.198
Cold Ischemia Time	1.006	0.002	2.56	0.010	1.001-1.010
Delayed Graft Function	1.770	0.063	16.00	< 0.001	1.650-1.898
Acute Rejection at 1 Year	1.782	0.089	11.59	< 0.001	1.616-1.965
No Induction Immunosuppression	0.987	0.036	−0.37	0.715	0.919-1.060	1.083	0.054	1.61	0.108	0.983-1.193

^*Tacrolimus and the interaction term between tacrolimus and time were also included in the multivariable model

^**Included as an interaction term along with duration of dialysis or diabetes, as appropriate