Table 3.
Univariate and multivariable logistic regression for high-grade cancer found on confirmatory biopsy.
| Univariate | Multivariable | |||||
|---|---|---|---|---|---|---|
| High-Grade Cancer | OR | 95% CI | p-Value | OR | 95% CI | p-Value |
| MRI result | ||||||
| No focal/dominant lesion | Ref. | Ref. | Ref. | Ref. | Ref. | Ref. |
| Focal/dominant lesion | 2.41 | 1.25–4.65 | 0.009 | 1.33 | 0.62–2.89 | 0.5 |
| PSA density (per 1 ng/ml/10 cm3) | 2.36 | 1.55–3.58 | <0.0001 | 2.03 | 1.22–3.37 | 0.006 |
| Percent positive cores from all cores (%) | 1.04 | 1.01–1.06 | 0.003 | 1.00 | 0.97–1.03 | 1 |
| Total tumor length from all positive cores (mm) | 1.48 | 1.33–1.65 | <0.0001 | 1.35 | 1.15–1.58 | 0.0002 |
| Percent cancer from all positive cores (%) | 1.06 | 1.04–1.08 | <0.0001 | 1.02 | 0.99–1.04 | 0.2 |