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. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: J Bone Miner Res. 2015 Aug 6;31(1):152–162. doi: 10.1002/jbmr.2591

Figure 6. Scanning electron microscopy (SEM) of adult mouse incisors.

Figure 6

(A–C) SEM analysis of incisor enamel in mice treated with PBS or Notch antibodies in sagittal views. (A’–C’) Magnified views of red-boxed regions (A–C). Red arrowheads point to primary enamel rods and yellow arrowheads point to inter-rod enamel. Note the enlarged inter-rod enamel in anti-N1N2 incisors (B,B') compared to controls. In anti-J1J2 incisors, note the interrupted primary rod enamel and smaller size of inter-rod enamel (C,C') compared to controls. These observations highlight distinct roles of N1N2 and J1J2 in incisor enamel formation. DEJ, dentin-enamel junction; N1, NOTCH1; N2, NOTCH2; J1, JAG1; J2, JAG2.