Ultrastructural aspects of ventral male prostate and female prostate of senile gerbil. Control group: (a) (male), (b) and (c) (female). We observed large nuclei (n) and deposit of lipofuscin in the cytoplasm (large white arrow) of the epithelium. Basal membrane (bm). Dense stroma with abundant collagen fibres (co), and smooth muscle cells (smc). EE/PRE group: (d) (male). Increase in lipofuscin deposit (lp), amount of vesicle (v), Golgi complex (g) in the cytoplasm. (e) (female). Observed the presence of vesicle (dashed white arrow) in the secretory cells (sc). Note the presence of fusion of the vesicles (fv) and alterations in the cellular adhesion (large arrow). a: 7750X; b: 3597X; c, d: 6000X; e: 4646X.