Table 5.

In vitro micronucleus test of hydrolysed flubendazole

Compound	Concentration (µg/ml)	Cytotoxicity (%)	Frequency of micronucleated binucleate cells (%)
Vehicle	–	–	0.65
HF	5.0	0%	0.5
HF	20.0	1.0%	0.65
HF	60.0	28.0%	0.50
HF	80.0	38.0.0%	0.95
HF	100.0	54.0%	0.50
Vinblastine	0.06	NM	9.25*
Mitomycin C	0.10	NM	27.8*

NM, not measured; HF, hydrolysed flubendazole.

*Statistically significant P < 0.05.