Table 8.
Compound | Concentration (µg/ml) | Cytotoxicity (%) | Frequency of micronucleated binucleate cells (%) |
---|---|---|---|
Albendazole | 0.00 | 0.0 | 0.45 |
0.04 | 11.0 | 0.45 | |
0.16 | 18.0 | 1.20* | |
0.70 | 32.0 | 4.20* | |
3.00 | 12.0 | 4.00* | |
Albendazole sulfoxide | 0.0 | 0.0 | 0.60 |
3.0 | 1.0 | 0.30 | |
10.0 | 3.0 | 1.85* | |
30.0 | 23.0 | 3.70* | |
40.0 | 20.0 | 5.50* | |
Flubendazole | 0.000 | 0.0 | 0.40 |
0.025 | 4.0 | 0.20 | |
0.100 | 2.0 | 0.40 | |
0.400 | 6.0 | 4.75* | |
2.00 | 24.0 | 5.30* |
*Statistically significant P < 0.05.