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. 2015 Oct 6;31(3):309–321. doi: 10.1093/mutage/gev070

Table 8.

In vitro tests of comparator benzimidazoles

Compound Concentration (µg/ml) Cytotoxicity (%) Frequency of micronucleated binucleate cells (%)
Albendazole 0.00 0.0 0.45
0.04 11.0 0.45
0.16 18.0 1.20*
0.70 32.0 4.20*
3.00 12.0 4.00*
Albendazole sulfoxide 0.0 0.0 0.60
3.0 1.0 0.30
10.0 3.0 1.85*
30.0 23.0 3.70*
40.0 20.0 5.50*
Flubendazole 0.000 0.0 0.40
0.025 4.0 0.20
0.100 2.0 0.40
0.400 6.0 4.75*
2.00 24.0 5.30*

*Statistically significant P < 0.05.