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. 2016 Apr 22;7:580. doi: 10.3389/fmicb.2016.00580

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Copyright © 2016 Maza and Suzuki.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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IL-6 (A) and IL-8 (B) levels in culture supernatants of A549 cells during interaction with H. capsulatum. A549 cells were incubated in the absence (C) or presence (Hc) of H. capsulatum yeasts for 5, 16 or 24 h. Culture supernatants were collected, and IL-6 and IL-8 levels were determined by ELISA. Values represent the mean of triplicate experiments ± the standard deviation. ^∗p < 0.01 and #p < 0.05 when compared to C of the related time period. Similar results were obtained from three independent experiments.