Table 1. Common lncRNAs which are enriched in the exosomes of all four prostate cancer cell lines (VCaP, LNCaP, DU145 and PC3).
Gene name | VCaP | LNCaP | DU145 | PC3 | Long ncRNA type |
---|---|---|---|---|---|
ENST00000501280 | 62.0 | 21.4 | 21.4 | 14.7 | bidirectional |
uc010bys.1 | 28.7 | 11.0 | 11.0 | 14.6 | intergenic |
uc001qgn.1 | 50.0 | 5.4 | 5.4 | 3.0 | intronic antisense |
ENST00000499690 | 15.4 | 16.2 | 16.2 | 8.5 | intronic antisense |
ENST00000453968 | 48.5 | 2.5 | 2.5 | 2.3 | intergenic |
G36642 | 46.0 | 3.0 | 3.0 | 2.2 | intronic antisense |
AK055500 | 39.1 | 3.5 | 3.5 | 6.1 | intergenic |
HIT000070262 | 44.2 | 2.7 | 2.7 | 2.1 | natural antisense |
ENST00000452932 | 11.8 | 9.5 | 9.5 | 7.7 | intergenic |
chr13:38754175-38773200+ | 25.6 | 3.7 | 3.7 | 2.8 | intergenic |
nc-HOXB1-156- | 7.4 | 8.4 | 8.4 | 2.6 | intergenic |
ENST00000471393 | 18.5 | 2.3 | 2.3 | 3.5 | intergenic |
ENST00000412906 | 20.0 | 2.2 | 2.2 | 2.1 | intronic antisense |
ENST00000392478 | 3.7 | 6.2 | 6.2 | 2.0 | intronic antisense |
AY927529 | 7.0 | 2.6 | 2.6 | 5.8 | exon-sense overlapping |
ENST00000426885 | 5.8 | 3.3 | 3.3 | 4.5 | Intergenic |
AK123811 | 2.3 | 3.7 | 3.7 | 4.9 | intergenic |
ENST00000402340 | 5.7 | 2.3 | 2.3 | 3.7 | intergenic |
ENST00000509526 | 4.9 | 2.3 | 2.3 | 3.4 | intergenic |
ENST00000412347 | 4.1 | 2.5 | 2.5 | 3.0 | intergenic |
chr9:137160729-137173954- | 3.8 | 2.4 | 2.4 | 2.8 | intergenic |
ENST00000411341 | 3.3 | 2.3 | 2.3 | 3.2 | intergenic |
ENST00000430245 | 2.8 | 2.9 | 2.9 | 2.4 | intronic antisense |
ENST00000508864 | 3.9 | 2.4 | 2.4 | 2.1 | intergenic |
uc001upm.2 | 2.2 | 2.0 | 2.0 | 4.3 | intergenic |
ENST00000500478 | 3.2 | 2.2 | 2.2 | 2.3 | intergenic |
The threshold cut-off was a fold change greater then 2. Fold change was defined as the ratio of normalized intensities between two samples (exosome versus cell), positive value indicates up-regulation.