Table 4. Overrepresentation of miRNA seed region motifs in highly enriched exosomal lncRNAs from the VCaP cell line.
| Motif | miRNA | Fold-change |
|---|---|---|
| CAGCCU | hsa-miR-762 | 10.39 |
| CUCCUG | hsa-miR-30b-3p | 8.57 |
| hsa-miR-1275 | 10.93 | |
| CCUCCC | hsa-miR-149-3p | 9.46 |
| AUUUUU | 28 distinct miRNAs | NA |
| GCCUCC | 13 distinct miRNAs | NA |
| CUGCCU | hsa-miR-363-5p | 8.54 |
| GCUGGG | hsa-miR-221-5p | 7.92 |
| UAUUUU | hsa-miR-20b-5p | 11.07 |
| hsa-miR-106b-5p | 11.51 | |
| hsa-miR-17-5p | 12.76 | |
| hsa-miR-18a-5p | 10.07 | |
| hsa-miR-106a-5p | 12.49 | |
| hsa-miR-93-5p | 11.98 | |
| hsa-miR-20a-5p | 11.85 | |
| hsa-let-7a-5p | 13.20 | |
| hsa-let-7b-5p | 14.52 | |
| hsa-let-7c-5p | 14.16 | |
| hsa-let-7d-5p | 12.22 | |
| hsa-let-7e-5p | 11.89 | |
| hsa-let-7g-5p | 9.29 | |
| hsa-let-7i-5p | 10.89 | |
| CCCAGC | 4 distinct miRNAs | NA |
| CCAGGC | 4 distinct miRNAs | NA |
| CCUGGG | 16 distinct miRNAs | NA |
| CCCAGG | 6 distinct miRNAs | NA |
| CCUCCU | hsa-miR-149-3p | 9.46 |
| CUGGGA | 11 distinct miRNAs | NA |
| GGCUGG | 21 distinct miRNAs | NA |
| CUCCCA | hsa-miR-1275 | 10.93 |
| hsa-miR-30b-3p | 8.57 | |
| AGGCUG | 10 distinct miRNAs | NA |
| CUCCAG | 8 distinct miRNAs | NA |
| CCUCAG | 11 distinct miRNAs | NA |
| UCCCAG | 18 distinct miRNAs | NA |
| UUUUUA | hsa-miR-1275 | 10.93 |
| hsa-miR-30b-3p | 8.57 | |
| CCUGCC | hsa-miR-1207-5p | 8.70 |
| GCCCAG | 9 distinct miRNAs | NA |
| UGGGAG | 13 distinct miRNAs | NA |
| GGGAGG | 20 distinct miRNAs | NA |
| CUUCCU | hsa-miR-149-3p | 9.46 |
| CUGCAG | 11 distinct miRNAs | NA |
| CUGGGC | hsa-miR-423-3p | 9.33 |
| UGCCUC | hsa-let-7g-5p | 9.29 |
| hsa-miR-3196 | 10.18 | |
| hsa-let-7e-5p | 11.89 | |
| hsa-let-7d-5p | 12.22 | |
| hsa-let-7c-5p | 14.16 | |
| hsa-let-7b-5p | 14.52 | |
| hsa-let-7a-5p | 13.20 | |
| CUCAGC | 7 distinct miRNAs | NA |
| UUUUCU | hsa-miR-185-5p | 9.25 |
| hsa-miR-149-3p | 9.46 |
Fold change of the miRNAs is shown in the last column. Note: All motifs listed in the table represent the perfect reverse complementarity to the seed region of specific miRNAs.