Table 2.

Likelihood of Having High Depressive Symptom Burden in Late Life According to Midlife PA Levels

		Midlife PA Group (n = 4,140)
		Inactive	Active
		(n = 2,848) 174 with HDEPS	(n = 1,292) 42 with HDEPS
		Odds Ratio (95% CI: low, high)
Six or higher late-life depressive symptoms	Model 1	Reference	0.57 (0.41, 0.81)
	Model 2	Reference	0.58 (0.41, 0.83)
	Model 3	Reference	0.57 (0.40, 0.82)
	Model 3 + MMSE	Reference	0.58 (0.41, 0.83)
	Model 3 + SP	Reference	0.61 (0.42, 0.86)
	Model 3 + MEM	Reference	0.59 (0.41, 0.84)
	Model 3 + EF	Reference	0.59 (0.41, 0.84)
	Model 3 + SP, MEM, and EF	Reference	0.61 (0.43, 0.86)

Notes: CI = confidence interval, HDEPS = high depressive symptoms; PA = physical activity.

Model 1 = adjusted for age, sex, and education. Model 2 = Model 1 + Midlife risk factors: body mass index (BMI), systolic blood pressure, current smoking, cholesterol, coronary event, never smoked, and self-reported stroke. Model 3 = Model 2 + antidepressant medication use. Model 3 + MMSE = Model 3 adjusted for MMSE. Model 3 + SP = Model 3 adjusted for speed of processing (SP). Model 3 + MEM = Model 3 adjusted for memory (MEM). Model 3 + EF = Model 3 adjusted for executive function (EF). Model 3 + SP, MEM & EF = Model 3 adjusted for all cognitive function (SP, MEM, and EF).