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. 2015 Jul 23;107(10):djv198. doi: 10.1093/jnci/djv198

Table 2.

Proportion of stages II and III colon cancer patients who received adjuvant chemotherapy by stage at diagnosis (n = 3757)*

Characteristics Proportion of patients receiving chemotherapy
Stage II (n = 1908) Stage III (n = 1849)
wt % 95 % CI wt % 95% CI
Overall 28.7 25.4 to 32.3 65.4 61.8 to 68.9
Year of diagnosis
 1990/1991 22.5 19.0 to 26.4 56.3 51.0 to 61.4
 1995 27.9 21.2 to 35.6 59.5 48.6 to 69.6
 2000 33.5 24.4 to 44.2 65.3 56.2 to 73.4
 2005 32.1 24.8 to 40.5 72.4 65.1 to 78.7
 2010 29.3 21.8 to 38.2 66.4 58.2 to 73.7
Age at diagnosis, y
 <55 59.5 48.6 to 69.5 84.5 78.6 to 89.0
 55–64 46.2 38.4 to 54.2 84.9 79.3 to 89.2
 65–74 29.9 23.9 to 36.6 72.9 65.4 to 79.3
 75–79 17.3 11.3 to 25.4 63.0 54.0 to 71.2
 ≥80 5.8 3.6 to 9.0 30.3 21.9 to 40.3
Race/ethnicity
 White non-Hispanic 28.1 23.9 to 32.6 65.5 60.8 to 70.0
 Black non-Hispanic 28.8 23.5 to 34.8 60.8 54.8 to 66.6
 Hispanic 34.4 27.3 to 42.3 65.0 54.7 to 74.1
 Other 29.8 23.0 to 37.6 71.0 62.1 to 78.6
Health insurance
 Private/HMO/VA/Other 31.2 26.9 to 35.7 67.0 62.7 to 71.1
 Medicaid 24.2 15.8 to 35.2 61.4 51.8 to 70.2
 Medicare 18.5 12.6 to 26.3 57.9 47.7 to 67.5
 None 43.3 28.0 to 60.0 73.6 55.2 to 86.3
 Unknown 39.9 19.8 to 64.2 76.0 50.6 to 90.7
Comorbidity score
 0 31.5 27.4 to 36.0 68.5 64.3 to 72.4
 1 23.1 17.2 to 30.4 64.0 56.5 to 70.9
 ≥2 16.8 7.2 to 34.2 33.6 22.0 to 47.6
Tumor extent
 T1-2 NA NA 76.9 66.9 to 84.5
 T3 24.8 21.7 to 28.3 65.4 61.4 to 69.2
 T4 53.6 41.7 to 65.2 58.0 47.6 to 67.8
Histologic grade
 Well/moderately differentiated 28.7 25.4 to 32.3 67.1 62.8 to 71.2
 Poorly/undifferentiated 27.3 20.2 to 35.7 61.2 53.7 to 68.2
 Unknown 37.6 24.2 to 53.2 65.0 49.8 to 77.6
Positive margins at surgery
 Yes 49.1 27.7 to 70.8 53.8 36.9 to 69.8
 No 28.3 24.7 to 32.2 66.5 62.8 to 69.9
 Unknown 24.7 17.4 to 33.9 62.2 47.1 to 75.3

* Proportions weighted by sampling fraction. Table excludes patients who did not undergo cancer-directed surgery (n = 20) or with missing or unknown chemotherapy agents (n = 82); patients who received preoperative chemotherapy (n = 6) are included. CI = confidence interval; NA = not applicable; wt = weighted.