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. 2016 Apr 22;6:24739. doi: 10.1038/srep24739

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(A) Superposition of five OBPs matching panels B-F in the same orientation. (B) Locusta migratoria OBP1 (PDB 4pt1)⁵⁵. This is a highly ranked structural homologue but has the conventional C-terminus, in this case a helix, coming across the bottom of the molecule to the right hand side as drawn; (C) Culex quinquefasciatus OBP (PDB 3ogn)³⁰ has the C-terminus going across the bottom in a similar position to L. migatoria; although its N-terminus does come across to the left hand side; (D) Anopholes gambiae OBP48 structure (PDB 4ij7)³⁴ has the C-terminus not coming across the bottom of the molecule and staying on the left as drawn, with the N-terminal coming across the bottom of the molecule as does (E) MvicOBP3 (PDB 4z39) and (F) Rhyparobia mader OBP (PDB 1org), although in this case the N-terminus does not block off the pocket fully.