Table I.
Search strategy in the review.
| Databasea | Step | Strategy |
|---|---|---|
| MEDLINE/PubMed, EMBASE and Web of Science | 1 | Explode ‘clinical-trial’/all subheadings |
| 2 | Clinical near trial | |
| 3 | Single | |
| 4 | Double | |
| 5 | Single, double or triple near blind or mask | |
| 6 | Random | |
| 7 | Control | |
| 8 | #1 or 2 or 3 or 4 or 5 or 6 or 7 | |
| 9 | EC = ‘HUMAN’ | |
| 10 | #8 and 9 | |
| 11 | Explode ‘brain-tumor’/all subheadings | |
| 12 | Malignant glioma | |
| 13 | Glioblastoma multiform | |
| 14 | Astrocytoma or anaplastic astrocytoma | |
| 15 | Avastin | |
| 16 | Brain tumor | |
| 17 | #11 or 12 or 13 or 14 or 15 or 16 | |
| 18 | Bevacizumab | |
| 19 | Temozolomide | |
| 20 | Radiotherapy | |
| 21 | #18 or 19 or 20 | |
| 22 | #10 and 17 and 21 |
a
Original search strategy has been adapted from the Ovid to Silver Platter version. The same principle was suitable for each database search (between January 1, 2000 and August 4, 2014).