Table I.
Characteristics of studies included in the present meta-analysis.
| Simple size | Case genotype | Control genotype | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| First Author | Year | Country | Ethnicity | Cases | Controls | GG | GT | TT | GG | GT | TT | Source of controls | Genotyping method | (Refs.) |
| Shete (France) | 2009 | USA | Caucasian | 1,374 | 1,579 | 0 | 418 | 885 | 25 | 421 | 1,133 | PB | Illumina | (14) |
| Shete (German) | 2009 | USA | Caucasian | 498 | 571 | 30 | 185 | 283 | 13 | 144 | 414 | PB | Illumina | (14) |
| Shete (Sweden) | 2009 | USA | Caucasian | 643 | 775 | 27 | 223 | 393 | 36 | 247 | 492 | PB | Illumina | (14) |
| Shete (UK) | 2009 | USA | Caucasian | 631 | 1,434 | 29 | 216 | 386 | 48 | 410 | 976 | PB | Illumina | (14) |
| Shete (US) | 2009 | USA | Caucasian | 1,246 | 2,235 | 60 | 451 | 735 | 72 | 667 | 1,496 | PB | Illumina | (14) |
| Schoemaker (Denmark) | 2010 | UK | Caucasian | 123 | 147 | 7 | 40 | 76 | 3 | 46 | 98 | PB | PCR | (13) |
| Schoemaker (Finland) | 2010 | UK | Caucasian | 97 | 95 | 16 | 34 | 47 | 6 | 31 | 58 | PB | PCR | (13) |
| Schoemaker (Sweden) | 2010 | UK | Caucasian | 199 | 372 | 6 | 63 | 130 | 14 | 117 | 241 | PB | PCR | (13) |
| Schoemaker (UK-North) | 2010 | UK | Caucasian | 375 | 617 | 16 | 122 | 237 | 27 | 156 | 434 | PB | Illumina, PCR | (13) |
| Schoemaker (UK-South) | 2010 | UK | Caucasian | 232 | 396 | 12 | 83 | 137 | 11 | 119 | 266 | PB | Illumina, PCR | (13) |
| Wang | 2011 | USA | Caucasian | 332 | 817 | 24 | 121 | 187 | 19 | 242 | 556 | HB | Illumina | (12) |
| Li | 2012 | China | Asian | 225 | 254 | 12 | 92 | 121 | 25 | 102 | 127 | HB | MassArray | (11) |
| Safaeian (NCI) | 2013 | USA | Caucasian | 322 | 385 | 17 | 123 | 182 | 11 | 107 | 267 | HB | Illumina | (10) |
| Safaeian (NIOSH) | 2013 | USA | Caucasian | 300 | 538 | 14 | 107 | 179 | 23 | 158 | 357 | PB | Illumina | (10) |
| Safaeian (PLCO) | 2013 | USA | Caucasian | 133 | 855 | 10 | 40 | 83 | 23 | 248 | 584 | PB | Illumina | (10) |
| Wibom | 2015 | Sweden | Caucasian | 560 | 560 | 36 | 174 | 350 | 6 | 163 | 391 | HB | PCR | (8) |
PB, population-based; HB, hospital-based; PCR, polymerase chain reaction; NCI, National Cancer Institute; NIOSH; National Institute for Occupational Safety and Health; PLCO, prostate, lung, colorectal and ovarian cancer screening trial.